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“Fast Track” nasogastric decompression of rectal cancer surgery
Ka Li, Zongguang Zhou, Zengrong Chen, Yi Zhang, Cun Wang
Frontiers of Medicine 2011, Volume 5, Issue 3, Pages 306-309 doi: 10.1007/s11684-011-0154-6
Keywords: fast track nasogastric decompression rectal cancer surgery
Synchronous rectal adenocarcinoma and anal canal adenocarcinoma
GU Jin, YAO Yunfeng, LI Jiyou, LU Aiping, WANG Hongyi
Frontiers of Medicine 2007, Volume 1, Issue 3, Pages 333-337 doi: 10.1007/s11684-007-0064-9
Keywords: CK7+/CK20+ resection different therapeutic strategy upper-third
Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 942-942 doi: 10.1007/s11684-021-0876-z
Progress and challenges in RET-targeted cancer therapy
Frontiers of Medicine 2023, Volume 17, Issue 2, Pages 207-219 doi: 10.1007/s11684-023-0985-y
Keywords: pralsetinib selpercatinib RET-alteration lung cancer thyroid cancer tumor-agnostic therapy drug
Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
Yun Zhang, Robert A. Weinberg
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 361-373 doi: 10.1007/s11684-018-0656-6
Keywords: epithelial-to-mesenchymal transition cancer metastasis cancer stem cell
Metformin for cancer prevention
Yonghua Yang
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 115-117 doi: 10.1007/s11684-011-0112-3
Orlistat induces ferroptosis-like cell death of lung cancer cells
Frontiers of Medicine 2021, Volume 15, Issue 6, Pages 922-932 doi: 10.1007/s11684-020-0804-7
Keywords: orlistat ferroptosis FAF2 lung cancer
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Frontiers of Medicine 2012, Volume 6, Issue 4, Pages 376-380 doi: 10.1007/s11684-012-0228-0
The forkhead transcription factors FOXO and FOXM1 have pivotal roles in tumorigenesis and in mediating chemotherapy sensitivity and resistance. Recent research shows that the forkhead transcription factor FOXM1 is a direct transcriptional target repressed by the forkhead protein FOXO3a, a vital downstream effector of the PI3K-AKT-FOXO signaling pathway. Intriguingly, FOXM1 and FOXO3a also compete for binding to the same gene targets, which have a role in chemotherapeutic drug action and sensitivity. An understanding of the role and regulation of the FOXO-FOXM1 axis will impact directly on our knowledge of chemotherapeutic drug action and resistance in patients, and provide new insights into the design of novel therapeutic strategy and reliable biomarkers for prediction of drug sensitivity.
Keywords: FOXO3a FOXM1 transcription factor cancer drug resistance tumorigenesis
Frontiers of Medicine doi: 10.1007/s11684-023-1050-6
Keywords: pancreatic cancer cancer screening single cell molecular alterations precancerous lesion therapy
Frontiers of Medicine 2023, Volume 17, Issue 1, Pages 18-42 doi: 10.1007/s11684-022-0976-4
Keywords: non-small cell lung cancer driver mutations treatment strategy resistant mechanism immune-checkpoint
Low-dose CT for lung cancer screening: opportunities and challenges
Hongbing Shen
Frontiers of Medicine 2018, Volume 12, Issue 1, Pages 116-121 doi: 10.1007/s11684-017-0600-1
Lung cancer is among the most frequently diagnosed cancers worldwide and the leading cause of cancerScreening for lung cancer coupled with earlier intervention has long been studied as an approach to mortalityOn the basis of this finding, LDCT has been recommended for lung cancer screening in high-risk populationsThis paper summarizes and discusses the main observations and challenges of LDCT screening for lung cancerComplementary biomarkers and technical improvement are expected in the field of lung cancer screening
Keywords: lung cancer low-dose computerized tomography early detection opportunities challenges
Developments in cancer prevention and treatment using traditional Chinese medicine
Hongsheng Lin, Jie Liu, Ying Zhang
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 127-133 doi: 10.1007/s11684-011-0137-7
Keywords: traditional Chinese medicine (TCM) cancer
Exploring the cancer genome in the era of next-generation sequencing
Hui Dong, Shengyue Wang
Frontiers of Medicine 2012, Volume 6, Issue 1, Pages 48-55 doi: 10.1007/s11684-012-0182-x
The emergence of next-generation sequencing technologies has led to dramatic advances in cancer genomeComprehensive analysis of cancer genomes through approaches of whole genome, exome, and transcriptomesequencing has significantly improved the understanding of cancer biology, diagnosis, and therapy.The present study briefly reviews the recent pioneering studies on cancer genome sequencing and provides
Keywords: next-generation sequencing cancer genome whole genome sequencing exome transcriptome
Intracellular and extracellular TGF-β signaling in cancer: some recent topics
Kohei Miyazono, Yoko Katsuno, Daizo Koinuma, Shogo Ehata, Masato Morikawa
Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 387-411 doi: 10.1007/s11684-018-0646-8
Keywords: TGF-β EMT lung cancer pancreatic cancer latent form immune function GARP
Dendritic cell vaccines in cancer immunotherapy: from biology to translational medicine
Hongmei Xu, Xuetao Cao
Frontiers of Medicine 2011, Volume 5, Issue 4, Pages 323-332 doi: 10.1007/s11684-011-0172-4
Title Author Date Type Operation
“Fast Track” nasogastric decompression of rectal cancer surgery
Ka Li, Zongguang Zhou, Zengrong Chen, Yi Zhang, Cun Wang
Journal Article
Synchronous rectal adenocarcinoma and anal canal adenocarcinoma
GU Jin, YAO Yunfeng, LI Jiyou, LU Aiping, WANG Hongyi
Journal Article
Midline2 is overexpressed and a prognostic indicator in human breast cancer and promotes breast cancer
Journal Article
Epithelial-to-mesenchymal transition in cancer: complexity and opportunities
Yun Zhang, Robert A. Weinberg
Journal Article
Role of the forkhead transcription factor FOXO-FOXM1 axis in cancer and drug resistance
Fung Zhao, Eric W.-F. Lam
Journal Article
Improving the prognosis of pancreatic cancer: insights from epidemiology, genomic alterations, and therapeutic
Journal Article
Treatment of advanced non-small cell lung cancer with driver mutations: current applications and future
Journal Article
Developments in cancer prevention and treatment using traditional Chinese medicine
Hongsheng Lin, Jie Liu, Ying Zhang
Journal Article
Exploring the cancer genome in the era of next-generation sequencing
Hui Dong, Shengyue Wang
Journal Article
Intracellular and extracellular TGF-β signaling in cancer: some recent topics
Kohei Miyazono, Yoko Katsuno, Daizo Koinuma, Shogo Ehata, Masato Morikawa
Journal Article